Introduction: nowadays, cow's milk is one of the most important and commonly used animal milk consumed by human and it is a unique source of food for all ages. When the milk is contaminated with heavy metals such as lead and cadmium, it is considered a threat to human. Lead and Cadmium poisoning cause adverse effects on human, which is more common in childhood period. This study aimed to investigate the Lead and Cadmium level in caw milk in Zabol.
Material & methods: Randomly, 100 samples of milk were directly collected from the farms cows of the 5 Zabol's areas that tested to determine Lead and Cadmium residues by using Association of Analytical Communities (A.O.A.C) protocol. The heavy metals were determined by using a Rayleigh atomic absorption spectrome equipped with hollow cathode lamps (HCL) at 283.3 nm for Lead (Pb) and at 228.8 nm for cadmium. The Kolmogorov-Smirnov test. The results were analyzed by SPSS software.
 Findings: It was indicated that the mean of lead level was 9.175± 2.581 ppb and for cadmium 4.557 ± 1.08 ppb in raw milk. P-values equal to 0.057(p<0.05) ppb for lead and was considered for cadmium was 0.435 (p<0.05) ppb. The standard levels for lead and cadmium were considered 1000 ppb and 10 ppb respectively Lead and cadmium contamination was less than standard in all milk samples. Discussion & Conclusion: The measuring of the samples showed that the Lead and Cadmium level were lower than the global standard, so all of the collected fresh milk was clean, pure and safe.