[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
Publication Ethics::
Peer Review Process::
Indexing Databases::
For Authors::
For Reviewers::
Subscription::
Contact us::
Site Facilities::
::
Google Scholar Metrics

Citation Indices from GS

AllSince 2019
Citations62733583
h-index2719
i10-index18478

..
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Registered in

AWT IMAGE

AWT IMAGE

..
:: Volume 14, Issue 2 (7-2006) ::
Journal of Ilam University of Medical Sciences 2006, 14(2): 1-9 Back to browse issues page
Role of Hyaluronan During Foliculogenesis of Mouse
Abstract:   (42760 Views)
Abstract Introduction:Hyaluronan is an extremely long glycosaminoglycan, which at variance with other glycosaminoglycans, is released into the extracellular. Both proteoglycans and hyaluronan influence many aspects of cell behavior by multiple interactions with other molecules.They synthesis change significantly during ovarian follicular development.This study was aimed to recognize of the structure of hyaluronan named glycosaminoglycans and also its alteration in different parts of follicular development during ovarian cycle. Materials & Methods: In this study, 60 mice with race N-MARI (wt 25-30gr) were prepared from Razi Institute. After adaptation of mice to laboratory conditions and reaching the maturity age, They were used in this study. After appearance of pudenda, which indicate ovarian cycle, their ovaries, were removed and changes in hyaluronan were studied using histochemical methods. Using Alcian Blue staining, pH=3.2, the hyaluronan in prepared tissue blocks from ovarian was evaluated. Findings: The observed changes proved that expression of hyaluronan was increased during folliculogenesis up to preovulatory stage. Hyaluronan synthesis increased in zona pellucida, base membrane and inner teca cells during ovarian cycle but it decreased in follicular cells and follicular fluid after antral stage. Conclusion: It can be concluded that expression of hyaluronan is necessary for expansion of cumulus-oopherous complex during foliculogenesis and ovulation, and also for increase of sperm motility during fertilization.
Keywords: Hyaluronan, Development, Ovary, Follicle, Mouse.
Full-Text [PDF 310 kb]   (5424 Downloads)    
Type of Study: Research | Subject: General
Received: 2009/01/28 | Published: 2006/07/15
Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Role of Hyaluronan During Foliculogenesis of Mouse. J. Ilam Uni. Med. Sci. 2006; 14 (2) :1-9
URL: http://sjimu.medilam.ac.ir/article-1-77-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 14, Issue 2 (7-2006) Back to browse issues page
مجله دانشگاه علوم پزشکی ایلام Journal of Ilam University of Medical Sciences
Persian site map - English site map - Created in 0.15 seconds with 40 queries by YEKTAWEB 4643